Optimal transport of two ions under slow spring-constant drifts

Slow axoplasmic transport under scrutiny.

The origin of axoplasmic proteins is central for the biology of axons. For over fifty years axons have been considered unable to synthesize proteins and that cell bodies supply them with proteins by a slow transport mechanism. To allow for prolonged transport times, proteins were assumed to be stable, i.e., not degraded in axons. These are now textbook notions that configure the slow transport ...

Homozygous state for Hb Constant Spring (slow-moving Hb X components).

Slow components of axonal transport: two cytoskeletal networks

We have identified two slowly moving groups of axonally transported proteins in guinea pig retinal ganglion cell axons (4). The slowest group of proteins, designated slow component a (SCa), has a transport rate of 0.25 mm/d and consists of tubulin and neurofilament protein. The other slowly transported group of proteins, designated slow components b (SCb), has a transport rate of 2-3 mm/d and c...

Two Constant-Factor-Optimal Realizations of Adaptive Heapsort

In this paper we introduce two efficient priority queues. For both, insert requires O(1) amortized time and extract-min O(lgn) worstcase time including at most lgn+O(1) element comparisons, where n is the number of elements stored. One priority queue is based on a weak heap (array-based) and the other on a weak queue (pointer-based). In both, the main idea is to temporarily store the inserted e...

Strategyproof Classification under Constant Hypotheses: A Tale of Two Functions

We consider the following setting: a decision maker must make a decision based on reported data points with binary labels. Subsets of data points are controlled by different selfish agents, which might misreport the labels in order to sway the decision in their favor. We design mechanisms (both deterministic and randomized) that reach an approximately optimal decision and are strategyproof, i.e...